Retrieve the source
Every record is pulled live from public registries and literature — not summarized from memory.
Clinical evidence engine for trial design
ClinGine™
The Clinical enGine that pulls source trial records and linked publications, then turns that evidence into endpoint strategy, safety intelligence, and traceable design rationale — so treatments reach patients sooner.
Scroll to watch the engine work
01 · The engine
A clinical engine powers up.
ClinGine™ spins up its turbine — pulling in the world's registered trial records and their linked publications from ClinicalTrials.gov, EU-CTR and PubMed.
02 · Evidence collides
Records and interventions collide and fuse.
Endpoints, outcomes, safety findings and design fields fuse into one standardized capsule of evidence you can trace back to its source.
03 · Reaching patients
That force accelerates trials toward patients.
Traceable design guidance helps teams build better trials, faster — so promising treatments reach the patients who need them sooner.
What is ClinGine
One engine between scattered trial evidence and a better protocol.
ClinGine draws in the world's registered trial records and their linked publications, fuses them into standardized evidence, and drives that force outward as design guidance you can trace to its source.
Source records
ClinicalTrials.gov + EU-CTR records and NCT-linked PubMed publications.
ClinGine engine
Parses endpoints, outcomes, safety, design and enrollment into standardized evidence.
Better trials & patients
Traceable recommendations that help researchers design trials that reach patients.
Standardize the evidence
Endpoints, outcomes and adverse events are normalized so precedent is comparable across trials.
Explain the rationale
Each recommendation shows why it is suggested, where evidence is weak, and what needs a statistician.
How this helps
From literature-search chaos to protocol-planning clarity.
Find precedent fast
Search by disease module, intervention, population, phase, keyword, and recruitment status.
Compare design choices
Review randomization, masking, phase, sample size, endpoints, outcomes, and safety terms.
Justify recommendations
See why a design or endpoint is suggested, where evidence is weak, and what needs biostatistical review.
PCOS, diabetes mellitus, obesity/overweight, endometriosis, and hypogonadism.
Every endpoint, outcome, and safety summary traces back to its source trial record or linked publication.
For students, researchers, CROs, and pharma teams who need prior evidence before designing a new trial.
Live backend · real records
ClinGine™ Evidence Workspace
Run a live query against ClinicalTrials.gov, EU-CTR and PubMed. Results are real, source-linked, and exportable.
Ready
matched records shown
median enrollment
common duration
endpoint evidence
recruitment timeline
Recommendation & Scientific Rationale
Run an analysis to generate design guidance.
Primary Endpoints
Click an item to view source trialsAdverse Events
Click an item to view source trialsSerious Adverse Events
Click an item to view source trials and publicationsSample-Size Planning Detail
Source Trials
Matched Trial Evidence
| Trial | Design | Sample | Endpoints | Outcomes / Safety |
|---|---|---|---|---|
| No trials loaded yet. | ||||
Evidence tableClinicalTrials.gov APIEU Clinical Trials RegisterPubMed-linked publications
Connected global registry searchesWHO ICTRPEU CTISCTRI IndiaISRCTNANZCTRChiCTRjRCT
Connected Global Registries
Reference sources checked alongside the evidence above. Table data comes from ClinicalTrials.gov + EU-CTR plus PubMed enrichment; WHO ICTRP and others are connected for global checking.Roadmap
ClinGine™ is being built as a broad clinical trial design workspace.
Across therapeutic areas, from endocrine and reproductive health outward.
PCOS, diabetes, obesity, endometriosis, hypogonadism
Search trial registries, linked publications, endpoints, sample-size precedent, outcomes, and adverse-event evidence for these live modules.
EU-CTR row-level source
European Union Clinical Trials Register rows are now merged into the evidence table alongside ClinicalTrials.gov.
Validated power calculator
Convert endpoint choices into formal sample-size calculations with effect size, variance, event rate, dropout, and allocation assumptions.
Beyond endocrine & reproductive health
Oncology, cardiovascular, neurology, immunology, and rare-disease modules can be integrated next.
Careers
Building at the intersection of clinical research, evidence science, and software.
We are shaping roles for clinical researchers, medical writers, biostatistics collaborators, evidence reviewers, and product engineers who care about scientifically reliable trial design support.
Clinical & evidence roles
Clinical researchers, medical writers, and evidence reviewers to curate disease modules and validate outputs.
Biostatistics
Collaborators to build the validated power calculator and endpoint-specific sample-size logic.
Product & engineering
Engineers who care about scientifically reliable, traceable trial-design support at scale.
Contact
For careers, collaborations, and clinical research partnerships.
To discuss ClinGine™, contribute to disease modules, explore academic collaborations, or share feedback from clinical research workflows, please contact: